Endocrine Abstracts

Objective: To analysis the clinical pathological characteristics and 131I curative responses of familial differentiated thyroid cancer(FDTC) and sporadic differentiated thyroid cancer(SDTC).Methods: A total of 112 FDTC patients(79 females, 33males, age(41.3±15.6)) and 1000 SDTC (658 females, 342males, (44.2±13.9)) who underwent 131I therapy in Department of Nuclear Medicine in our hospital between January 2011 and July 2021 we...

Background: There are no definite recommendations on the optimal dosage of initiating adjuvant radioactive iodine (RAI) therapy for intermediate-risk differentiated thyroid cancer (DTC) patients in current relevant guideline. This study aimed to investigate the response of intermediate-risk DTC patients with a low (3.7GBq) or high RAI dose (5.55GBq).Methods: Propensity score matching was performed to control for baseline characteristics. A total of 476 p...

Objective: To explore the association between body mass index (BMI) and plasma glucose level with pathological features and clinical outcomes of differentiated thyroid cancer (DTC).Methods: Clinical data of 1264 consecutive DTC patients treated with total thyroidectomy and enrolled at the time of the first 131I treatment from April 2016 to July 2020. The clinicopathological findings were compared in the groups were categorized according to BMI...

Thyroid papillary carcinoma (PTC) is the most common endocrine tumor, Hashimoto’s thyroiditis (HT) is considered to be closely related to PTC pathogenesis, but their relationship still needs verification and exploration. Aim of the study. To analyze the differences and similarities of the metabolic mechanism of thyroid papillary carcinoma in normal and HT background, and to explore the relationship between HT and PTC. The Ultra performance liquid chromatography-q...